WebNational Center for Biotechnology Information WebMar 7, 2024 · INTRODUCTION. Daptomycin is a lipopeptide antimicrobial with activity against gram-positive organisms, including antimicrobial-resistant pathogens such as …
Daptomycin Article - StatPearls
WebNov 3, 2024 · In the package insert, recommended dosing for IHD is 4 or 6 mg/kg every 48 hours, which does not align with thrice-weekly IHD. 9 Some studies suggest increasing the dose by 50% during the 72-hour interdialytic period. 10,11 However, this is based on a dose of 6 mg/kg (i.e., 6/6/9) and it is not clear if this is necessary with higher doses. WebMar 20, 2013 · One (0.5%) patient received daptomycin three times weekly, an alternative, unapproved dosing interval for patients on three times weekly dialysis (48 h–48 h–96 h). Sixty-four (29%) patients received at least a proportion … shrubbery for shaded areas
Cubicin (daptomycin) dosing, indications, interactions, adverse …
WebOnce daily dosing: goal peak 35–60; goal trough <4. Consult Hartford Nomogram Conventional dosing: goal peak 25–35 for serious infections; 15–20 for UTI goal trough:<5-8 CrCl >60 CrCl 40–60: CrCl 20–40 CrCl < 20 Conventional dosing 5 – 7.5 mg/kg q8h 5 – 7.5 mg/kg q12h 5 – 7.5 mg/kg q24h 5 mg/kg High-dose load, then extended- WebApr 2, 2024 · Vancomycin (VCM) and daptomycin (DAP) are standard therapies for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, despite concerns regarding clinical utility and growing resistance. Linezolid (LZD) affords superior tissue penetration to VCM or DAP and has been successfully used as salvage therapy for persistent MRSA … WebProvide loading dose then dose patients 10-15 mg/kg q24h and adjust accordingly to obtain serum concentrations within desired range 1, 11 Abbreviations: EI, extended infusion (4 … theory belted turtleneck sweater dress