Cytoplasmic aconitate hydratase-like

WebAug 4, 2024 · Therefore, it’s possible cytoplasmic aconitate hydratase may regulate energy metabolism during oogenesis as well. Evidence of cytoplasmic aconitate hydratase abundance changing in response to low pH has been documented in C. gigas, which implies that low pH alters energy metabolism . Energy metabolism would be … WebWe show that PP2A-B'γ physically interacts with the cytoplasmic form of aconitase, a central metabolic enzyme functionally connected with mitochondrial respiration, oxidative stress responses and regulation of cell death in plants. Furthermore, PP2A-B'γ impacts ROS homeostasis by controlling the abundance of specific alternative oxidase ...

Cytoplasmic aconitate hydratase DrugBank Online

WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves dehydration followed by hydration. Although citrate is a symmetric molecule, aconitase works specifically on the OAA end of citrate, not the end derived from acetyl ... WebThis paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by … css image stretch to fit https://ardingassociates.com

Biology Free Full-Text Aconitase: To Be or not to Be Inside

WebPredicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including adaxial cell; heart tube; musculature system; nervous system; and pronephric duct. Human ortholog(s) of this … WebCytoplasmic aconitate hydratase Synonyms. 4.2.1.3; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; IRE-BP 1; IREB1; Iron regulatory protein 1; Iron-responsive element-binding protein 1; IRP1; Gene Name ACO1 Organism Humans Amino acid … WebDec 23, 2003 · Nevertheless, little is known regarding the response of aconitase to pro-oxidants within intact mitochondria. In the present study, we provide evidence that aconitase is rapidly inactivated and subsequently reactivated when isolated cardiac mitochondria are treated with H (2)O (2). Reactivation of the enzyme is dependent on the presence of the ... css image stretch to fit div

Characterization of aconitate hydratase from mitochondria and …

Category:Redox-dependent modulation of aconitase activity in intact …

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Cytoplasmic aconitate hydratase-like

Tandem mass tag-based quantitative proteomic profiling

WebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. … WebJan 4, 2024 · fumarate hydratase Antibody (J-13) is a mouse monoclonal IgG 2b κ, cited in 58 publications, provided at 100 µg/ml. raised against recombinant fumarate hydratase of human origin. recommended for detection of precursor mitochondrial and cytoplasmic mature chains of fumarate hydratase of human origin by WB, IP, IF, IHC (P) and ELISA.

Cytoplasmic aconitate hydratase-like

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WebThe activity of the iron-dependent enzyme cytosolic aconitase (c-aconitase) is increased by iron. The conversion of citrate to isocitrate by c-aconitase is the first step in a three … WebAconitate Hydratase. Aconitate hydratase (aconitase, EC4.2.1.3) is both an important Krebs cycle enzyme and a cytosolic iron sensor as described above. From: Nutrient …

WebAug 1, 1988 · This paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by BALB/C mice. The results show a ... WebNX_P21399 - ACO1 - Cytoplasmic aconitate hydratase - Localization. Bifunctional iron sensor that switches between 2 activities depending on iron availability (PubMed:1946430, PubMed:1281544, PubMed:8041788). Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration …

WebKEGG Orthology (KO) [BR:gsj00001] 09100 Metabolism 09101 Carbohydrate metabolism 00020 Citrate cycle (TCA cycle) 114372894 00630 Glyoxylate and dicarboxylate metabolism Aconitase (aconitate hydratase; EC 4.2.1.3) is an enzyme that catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox-active process. • Citric acid • Aconitic acid

WebJul 30, 1999 · IRP1 is a cytoplasmic aconitase when it contains a [4Fe-4S] cluster and an RNA-binding protein after complete removal of the metal center by an unknown mechanism. Human IRP1, obtained as the pure recombinant [4Fe-4S] form, is an enzyme as efficient toward cis-aconitate as the homologous mitochondrial aconitase.

WebJul 8, 2024 · Enzymatic activity of aconitate hydratase (aconitase, EC 4.2.1.3) from the rat heart is localized in the cytoplasm (65%) and mitochondria (35%). Cytoplasmic and … earling 2020WebSearch Result : 7756 hits. Entry KO len SW-score(margin) bits identity overlap best(all earlingbusch truckingWebJul 12, 2024 · After the discovery in 1967 of plant glyoxysomes, aconitase, one the five enzymes involved in the glyoxylate cycle, was thought to be present in the organelles, and although this was found not to be the case around 25 years ago, it is still suggested in some textbooks and recent scientific articles. Genetic research (including the study of mutants … css image strokeWebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves … css image style fitWebCytoplasmic aconitate hydratase Kind protein Organism Humans Protein. Name UniProt ID; Cytoplasmic aconitate hydratase: P21399: Details: Drug Relations Drug Relations. DrugBank ID Name Drug group Pharmacological action? Actions Details; DB06757: Manganese: approved, nutraceutical: unknown: inhibitor: Details: css image style coverWebImmunocytochemistry/ Immunofluorescence: Aconitase 1 Antibody [NBP1-87677] - Staining of human cell line U-2 OS shows localization to cytosol & mitochondria. Antibody staining is shown in green. Immunohistochemistry-Paraffin: Aconitase 1 Antibody [NBP1-87677] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. css image stylingWebMay 27, 1998 · AH, aconitate hydratase (EC.4.2.1.3) NAD + –ICDH, NAD +-specific isocitrate dehydrogenase (EC.1.1.1.41) ... Some plants, like Kalanchoe leaves are unable to accumulate large amounts of isocitrate, ... The oxidation of cytoplasmic NAD(P)H when complex I in the electron transport chain is inhibited can be performed by rotenone … css image style examples