WebAug 4, 2024 · Therefore, it’s possible cytoplasmic aconitate hydratase may regulate energy metabolism during oogenesis as well. Evidence of cytoplasmic aconitate hydratase abundance changing in response to low pH has been documented in C. gigas, which implies that low pH alters energy metabolism . Energy metabolism would be … WebWe show that PP2A-B'γ physically interacts with the cytoplasmic form of aconitase, a central metabolic enzyme functionally connected with mitochondrial respiration, oxidative stress responses and regulation of cell death in plants. Furthermore, PP2A-B'γ impacts ROS homeostasis by controlling the abundance of specific alternative oxidase ...
Cytoplasmic aconitate hydratase DrugBank Online
WebAconitase is an iron–sulfur protein that isomerizes citrate to isocitrate through the enzyme-bound intermediate cis -aconitate. The two-step reaction is reversible and involves dehydration followed by hydration. Although citrate is a symmetric molecule, aconitase works specifically on the OAA end of citrate, not the end derived from acetyl ... WebThis paper describes the characterization of aconitate hydratase (EC 4.2.1.3) in cytoplasmic and mitochondrial extracts from Ehrlich ascites tumor cells carried by … css image stretch to fit
Biology Free Full-Text Aconitase: To Be or not to Be Inside
WebPredicted to enable 4 iron, 4 sulfur cluster binding activity and aconitate hydratase activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including adaxial cell; heart tube; musculature system; nervous system; and pronephric duct. Human ortholog(s) of this … WebCytoplasmic aconitate hydratase Synonyms. 4.2.1.3; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; IRE-BP 1; IREB1; Iron regulatory protein 1; Iron-responsive element-binding protein 1; IRP1; Gene Name ACO1 Organism Humans Amino acid … WebDec 23, 2003 · Nevertheless, little is known regarding the response of aconitase to pro-oxidants within intact mitochondria. In the present study, we provide evidence that aconitase is rapidly inactivated and subsequently reactivated when isolated cardiac mitochondria are treated with H (2)O (2). Reactivation of the enzyme is dependent on the presence of the ... css image stretch to fit div