WebApr 28, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin … WebOct 5, 2006 · If the DCAF proteins represent a family of substrate receptors for DDB1–CUL4A, then they might share a common DDB1-docking motif, analogous to the substrate receptors of other cullin E3 ...

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WebMay 23, 2016 · Cullin-2 is a member of the Cullin family, and it serves as a scaffold protein for Elongin B and C, Rbx1 and various substrate recognition receptors to form E3 ubiquitin ligases. Main body of the abstract First, the composition, structure and the regulation of Cullin-2 based E3 ubiquitin ligases were introduced. WebThere are at least eight Cullin family members. Among them, Cullin-2 forms a functional E3 ligase complex with elongin B, elongin C, RING-box protein 1 (RBX1, also called ROC1), as well as the substrate recognition subunit (SRS) to promote the substrate ubiquitination and degradation. porsche 911 key fob cover

Frontiers Chromatin-Bound Cullin-Ring Ligases: Regulatory …

WebCullin 4B Polyclonal Antibody, Invitrogen™-Rabbit Polyclonal Antibody Achetez Cullin 4B Polyclonal Antibody, Invitrogen™ sur Fishersci.fr WebThe Olympic coven, more commonly known as the Cullen family, and also known as Cullen clan, or Cullen coven, is a coven of vegetarian vampires. It consists of Carlisle , … WebCullin 3 (CUL3) is the scaffold of Cullin3 Ring E3-ligases (CRL3s), which use various BTB-adaptor proteins to ubiquitinate numerous substrates targeting their proteasomal degradation. CUL3 mutations, responsible for a severe form of familial hyperkalemia and hypertension (FHHt), all result in a deletion of exon 9 (amino-acids 403-459) (CUL3 … sharps box collection havering