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Polycythemia vera (PV) is a blood disorder in which the body makes too many red blood cells. It's one in a family of diseases called myeloproliferative disorders. In these diseases, bone marrow the spongy tissue inside bones where blood cells are made is affected by a type of chronic leukemia that causes it to … See more What is the latest research and treatment for polycythemia vera? Treatment of PV focuses on controlling symptoms and decreasing the risk of blood clots or bleeding. Therapies … See more In its early stages, PV may not cause symptoms. Due to the excess red blood cells, though, some people may eventually develop skin itchiness and redness, headaches, dizziness, shortness of breath, and numbness, … See more Exactly why PV develops is still unclear. But researchers know more about the cause of the disease now than in the past. In 2005, researchers found that a change (mutation) in a gene that affects the protein JAK2 … See more Over the long term, PV may progress to myelofibrosis, a disorder that involves scarring in the bone marrow, disruption of the production of blood cells, and can lead to enlargement of the spleen and liver. PV can also progress to … See more WebJan 22, 2024 · Pathology 31 years experience Yes.: In some instances, a person may produce too many red blood cells. An example of a disease like this is polycythema vera. This is an abnormal bone marrow condition (a myeloproliferative disorder) in which the patient's bone marrow makes too many red blood cells. rdp trusted certificate